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48 p, 8.9 MB The first crystal structure of human RNase6 reveals a novel substrate binding and cleavage site arrangement / Prats, Guillem, 1942- (Universitat Autònoma de Barcelona. Departament de Bioquímica i de Biologia Molecular) ; Arranz Trullén, Javier (Universitat Autònoma de Barcelona. Departament de Bioquímica i de Biologia Molecular) ; Blanco, José A. (Universitat Autònoma de Barcelona. Departament de Bioquímica i de Biologia Molecular) ; Pulido, Daniel. (Imperial College London) ; Nogués Bara, Maria Victòria (Universitat Autònoma de Barcelona. Departament de Bioquímica i de Biologia Molecular) ; Moussaoui, Mohammed. (Universitat Autònoma de Barcelona. Departament de Bioquímica i de Biologia Molecular) ; Boix i Borràs, Esther (Universitat Autònoma de Barcelona. Departament de Bioquímica i de Biologia Molecular)
Human RNase 6 is a cationic secreted protein that belongs to the RNase A superfamily. Its expression is induced in neutrophils and monocytes upon bacterial infection, suggesting a role in host defence. [...]
2016 - 10.1042/BCJ20160245
The Biochemical journal, 2016  
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